3-Bromofuro[3,4-b]pyridine-5,7-dione(CAS: 98278-78-5)

3-Bromofuro[3,4-b]pyridine-5,7-dione is a crystalline solid with a molecular weight of approximately 277.02 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and chloroform. This compound is highly reactive and can undergo bromination and other electrophilic aromatic substitution reactions.

3-Bromofuro[3,4-b]pyridine-5,7-dione is synthesized through bromination of furo[3,4-b]pyridine-5,7-dione. Commonly, this is achieved by treating the furo[3,4-b]pyridine-5,7-dione with bromine in the presence of a Lewis acid catalyst like aluminum tribromide to achieve high selectivity and yield.

3-Bromofuro[3,4-b]pyridine-5,7-dione is primarily used in the pharmaceutical industry for the synthesis of various drug intermediates. It also finds applications in the semiconductor industry, particularly in the development of organic semiconductors for solar cells and LEDs.

When handling 3-Bromofuro[3,4-b]pyridine-5,7-dione, it is essential to use appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated fume hood to minimize exposure. In case of a spill, immediately contain it and follow the spill cleanup procedures outlined in the Material Safety Data Sheet (MSDS/SDS).