1-[4-(Aminomethyl)phenyl]ethanone(CAS: 87171-25-3)

1-[4-(Aminomethyl)phenyl]ethanone is a colorless to yellow liquid at room temperature with a molecular weight of approximately 216.27 g/mol. It has a solubility of up to 10 g/L in water and is soluble in common organic solvents like ethanol and acetone. The compound has moderate reactivity, particularly towards nucleophiles due to the aminomethyl group.

1-[4-(Aminomethyl)phenyl]ethanone is commonly synthesized via the reaction of 4-(aminomethyl)benzaldehyde with ethanol in the presence of an acid catalyst such as hydrochloric acid. The reaction is conducted at room temperature, yielding a high selectivity and moderate to good yield.

1-[4-(Aminomethyl)phenyl]ethanone is primarily used in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also utilized in the polymer industry for the production of specialty polymers, and in the sensor industry for the development of gas sensing materials.

When handling 1-[4-(Aminomethyl)phenyl]ethanone, it is essential to wear personal protective equipment such as gloves, goggles, and a lab coat. The compound should be stored in a closed container and in a well-ventilated area. Spills should be handled with appropriate absorbent materials, and the area should be thoroughly cleaned. Always refer to the Safety Data Sheet (SDS) for detailed safety information.