N,N'-1,3-Phenylenediacetamide(CAS: 10268-78-7)

N,N'-1,3-Phenylenediacetamide is a white crystalline powder with a molecular weight of approximately 198.18 g/mol. It is slightly soluble in water and ethanol. It has limited reactivity under normal conditions but can undergo hydrolysis under acidic or basic conditions. The compound is stable under normal storage conditions but should be protected from prolonged exposure to moisture and strong acids or bases.

N,N'-1,3-Phenylenediacetamide is typically synthesized through the reaction of phenyldiacetamide with phenol, followed by an amidation step. The synthesis involves condensation of phenol with phenyldiacetamide in the presence of a catalyst such as sodium hydroxide. The yield is around 85-90%, and the method is selective and efficient.

N,N'-1,3-Phenylenediacetamide is mainly used in the pharmaceutical industry for the synthesis of certain drug intermediates. It also finds applications in the polymer industry, where it serves as a monomer for the preparation of special polymers. Additionally, it is used in the manufacturing of sensors and as a precursor in semiconductor technology.

When handling N,N'-1,3-Phenylenediacetamide, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from heat sources and direct sunlight. In case of spills, they should be cleaned up immediately using appropriate spill kits. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.