2-[2-Fluoro-4-(1H-1,2,4-triazol-1-yl)phenyl]-1,3-di(1H-1,2,4-triazol-1-yl)-2-propanol(CAS: 871550-15-1)

2-[2-Fluoro-4-(1H-1,2,4-triazol-1-yl)phenyl]-1,3-di(1H-1,2,4-triazol-1-yl)-2-propanol is a crystalline solid with a molecular weight of approximately 472.4 g/mol. It has low solubility in water but is more soluble in organic solvents like Dimethylformamide (DMF) and Dimethylsulfoxide (DMSO). This compound is highly reactive, showing good reactivity towards nucleophiles. It is stable under normal storage conditions but should be stored in a cool, dark place to preserve its properties.

2-[2-Fluoro-4-(1H-1,2,4-triazol-1-yl)phenyl]-1,3-di(1H-1,2,4-triazol-1-yl)-2-propanol is synthesized via a multi-step process involving the condensation of 2-fluoro-4-(1H-1,2,4-triazol-1-yl)phenyl isocyanate with 1,3-di(1H-1,2,4-triazol-1-yl)propan-2-ol. This reaction is catalyzed by a mild base, such as triethylamine, and proceeds with good yield and high selectivity. The final product is purified by recrystallization from organic solvents.

2-[2-Fluoro-4-(1H-1,2,4-triazol-1-yl)phenyl]-1,3-di(1H-1,2,4-triazol-1-yl)-2-propanol is primarily used in the pharmaceutical industry for its medicinal properties. It also finds application in the development of sensors and semiconductors due to its unique chemical structure, which provides excellent reactivity and stability.

Handling 2-[2-Fluoro-4-(1H-1,2,4-triazol-1-yl)phenyl]-1,3-di(1H-1,2,4-triazol-1-yl)-2-propanol requires specific laboratory safety measures. It should be handled in a well-ventilated area, preferably in a fume hood. Personal protective equipment (PPE) including gloves, goggles, and lab coat should be worn. Spills should be carefully cleaned up using appropriate absorbing materials, and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed instructions and emergency procedures.