1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea(CAS: 13909-09-6)

1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea is a crystalline compound with a molecular weight of approximately 313.08 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. The compound is known for its reactivity towards nucleophiles and can undergo substitution reactions under specific conditions.

1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea is usually synthesized through a multi-step process involving the reaction of 2-chloroethylamine with 3-(4-methylcyclohexyl)urea. The synthesis often requires the use of a protecting group to control the reactivity of the functional groups, and the final product is obtained with a yield of about 70%.

1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea is primarily used in the pharmaceutical industry for the development of anti-cancer drugs. It is also utilized in the research of chemical biology and medicinal chemistry. Its structural features make it relevant for studies in synthetic chemistry and organic synthesis.

Handling 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbent materials and the area should be thoroughly washed down. Consult the Safety Data Sheet (SDS) for detailed procedures and emergency response information.