(2-Methylphenyl)boronic acid(CAS: 16419-60-6)

(2-Methylphenyl)boronic acid is a solid, crystalline compound with a molecular weight of approximately 164.22 g/mol. It has a melting point of 145-149°C and is sparingly soluble in water. Chemically, it is reactive towards electrophiles and can participate in Suzuki coupling reactions. It is also known for its moderate solubility in common organic solvents such as ethanol and acetonitrile.

(2-Methylphenyl)boronic acid is typically synthesized via the reduction of 2-methylphenylboronic ester with a reducing agent such as sodium borohydride. This process yields a high purity product with good yield, making it a common method for obtaining this compound in the laboratory and industrial settings.

(2-Methylphenyl)boronic acid is widely used in the pharmaceutical industry for the synthesis of various drugs, particularly in medicinal chemistry and drug discovery. It is also utilized in the polymer industry for the preparation of functional polymers, as well as in the electronics industry for applications involving sensors and semiconductors.

When handling (2-Methylphenyl)boronic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety glasses. Handling should be performed in a well-ventilated area or a fume hood. In case of a spill, it should be cleaned up immediately using appropriate methods and materials. For detailed safety information, consult the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS).