4-Bromo-6-chloronicotinic acid(CAS: 1256834-13-5)

4-Bromo-6-chloronicotinic acid (CAS: 1256834-13-5) is a crystalline solid with a molecular weight of approximately 228.03 g/mol. It has a solubility of about 0.13 g/L in water. Chemically, it is reactive towards basic solutions and susceptible to hydrolysis. It is not flammable but can undergo redox reactions.

4-Bromo-6-chloronicotinic acid is typically synthesized through the bromination and chlorination of nicotinic acid. This process involves the use of bromine and chlorine as reagents. The reaction is carried out under reflux conditions with a suitable solvent. The yield is generally around 75-85%, with good selectivity for the desired product.

4-Bromo-6-chloronicotinic acid finds applications in pharmaceutical industries for the synthesis of certain drugs, and in analytical chemistry for the development of sensors. It is also used in the preparation of other organic compounds and in the field of organic electronics.

When handling 4-Bromo-6-chloronicotinic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed information on safe handling and storage.