10-Hydroxy-1-(2-hydroxy-3,4-dimethoxy-6-methylphenyl)-1-decanone(CAS: 104966-97-4)

10-Hydroxy-1-(2-hydroxy-3,4-dimethoxy-6-methylphenyl)-1-decanone is a clear to pale yellow liquid at room temperature. It has a molecular weight of approximately 332.3 g/mol. The compound is sparingly soluble in water but miscible with ethanol and acetone. It is moderately reactive, particularly towards nucleophiles and bases, making it suitable for various chemical transformations. It is also prone to photochemical degradation under UV light.

10-Hydroxy-1-(2-hydroxy-3,4-dimethoxy-6-methylphenyl)-1-decanone can be synthesized through a multi-step process involving the preparation of the phenolic intermediate, followed by its coupling with a decanone derivative. The synthesis typically employs Pd/C catalysis for the cross-coupling reaction. The reaction is highly selective and yields up to 85% of the desired product, with mild conditions ensuring high purity.

10-Hydroxy-1-(2-hydroxy-3,4-dimethoxy-6-methylphenyl)-1-decanone is primarily used in the pharmaceutical industry for the synthesis of drug intermediates. It is also utilized in the electronics industry for the development of organic semiconductors and photovoltaic materials. Additionally, it is employed in the polymer industry as a monomer for the production of functional polymers with specific optical and electronic properties.

When handling 10-Hydroxy-1-(2-hydroxy-3,4-dimethoxy-6-methylphenyl)-1-decanone, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up immediately using appropriate absorbents, and the area should be thoroughly washed down. The Safety Data Sheet (SDS) should be consulted for detailed emergency procedures and storage recommendations.