1-(4-Chlorophenyl)-6-methyl-4-oxo-1,4-dihydro-3-pyridazinecarboxylic acid(CAS: 68254-10-4)

1-(4-Chlorophenyl)-6-methyl-4-oxo-1,4-dihydro-3-pyridazinecarboxylic acid is a solid with a crystalline form. Its molecular weight is approximately 273.08 g/mol. It has a moderate solubility in water and organic solvents. This compound exhibits low reactivity under normal conditions but can undergo hydrolysis under acidic or basic conditions. It is an important intermediate in the synthesis of pharmaceuticals and other chemicals.

1-(4-Chlorophenyl)-6-methyl-4-oxo-1,4-dihydro-3-pyridazinecarboxylic acid is typically synthesized through a multi-step process involving the coupling of methyl 4-chlorobenzoyl chloride with 6-methyl-4-oxo-1,4-dihydro-3-pyridazinecarboxylic acid. The reaction proceeds in the presence of a suitable base, such as sodium bicarbonate, and a solvent like dichloromethane. The process yields a high purity product with a good yield of 75-80%.

1-(4-Chlorophenyl)-6-methyl-4-oxo-1,4-dihydro-3-pyridazinecarboxylic acid is widely used in the pharmaceutical industry as a key intermediate in the synthesis of various drugs. It also finds applications in the polymer industry, where it is used in the development of special polymers. Additionally, it is utilized in sensor technology and semiconductor manufacturing for its unique chemical properties.

When handling 1-(4-Chlorophenyl)-6-methyl-4-oxo-1,4-dihydro-3-pyridazinecarboxylic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a fume hood to minimize exposure. In case of a spill, it should be cleaned up immediately using appropriate absorbent materials and disposed of according to local regulations. Always refer to the safety data sheet (SDS) for detailed handling instructions and emergency procedures.