(3S)-3-Amino-3-(3-thienyl)propanoic acid(CAS: 773050-73-0)

(3S)-3-Amino-3-(3-thienyl)propanoic acid is a crystalline solid with a molecular weight of approximately 184.24 g/mol. It has a melting point of around 220-225°C and is slightly soluble in water. This compound is known for its reactivity, particularly with nucleophiles and bases. It is also mildly acidic due to the carboxylic acid group.

(3S)-3-Amino-3-(3-thienyl)propanoic acid can be synthesized through a multi-step process. Commonly, it is prepared by reacting thioacetamide with an amine, followed by a coupling reaction with an appropriate aldehyde or ketone. Key steps include the use of organic solvents and protecting group strategies to ensure high selectivity and yield.

(3S)-3-Amino-3-(3-thienyl)propanoic acid finds applications in the pharmaceutical industry for drug synthesis, particularly in the development of new drugs targeting specific receptors. It is also used in the polymer industry as a monomer for creating functional polymers with unique properties. Additionally, it is utilized in the production of sensors and semiconductors due to its chemical functionality.

When handling (3S)-3-Amino-3-(3-thienyl)propanoic acid, it is essential to use appropriate personal protective equipment (PPE), including gloves and safety goggles. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Proper spill clean-up procedures should be followed, and the substance should be disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.