2-Chloro-4,6-di(4-morpholinyl)-1,3,5-triazine(CAS: 7597-22-0)

2-Chloro-4,6-di(4-morpholinyl)-1,3,5-triazine is a crystalline solid with a molecular weight of approximately 306.75 g/mol. It is slightly soluble in water and more soluble in organic solvents. Chemically, it is relatively stable but can react with strong bases and reducing agents. It is a potent inhibitor of DNA topoisomerases and has been studied for its anticancer properties.

2-Chloro-4,6-di(4-morpholinyl)-1,3,5-triazine can be synthesized via a multi-step reaction involving the condensation of 4,6-bis(4-morpholinyl)-1,3,5-triazine with chloroacetic acid followed by a cyclization step. The reaction is typically carried out in the presence of a base such as sodium hydroxide and yields around 85% product with good selectivity.

2-Chloro-4,6-di(4-morpholinyl)-1,3,5-triazine is used in the pharmaceutical industry as an anticancer drug candidate. It also finds applications in the semiconductor industry for its role as a dopant and in the development of organic sensors due to its unique electronic properties.

When handling 2-Chloro-4,6-di(4-morpholinyl)-1,3,5-triazine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up using a suitable absorbent material, and the area should be thoroughly ventilated. Always consult the Material Safety Data Sheet (MSDS) for specific handling and disposal instructions.