(6-methoxycarbonyl-3-pyridyl)boronic acid(CAS: 1072945-86-8)

(6-methoxycarbonyl-3-pyridyl)boronic acid is a white crystalline solid with a molecular weight of approximately 263.22 g/mol. It has a solubility of about 0.1 g/L in water and is slightly soluble in organic solvents. It is known for its reactivity in boronate ester formation and its stability in acidic solutions.

(6-methoxycarbonyl-3-pyridyl)boronic acid is commonly synthesized via the reaction of 6-methoxycarbonyl-3-pyridineboronic acid with lithium or sodium hydroxide. The synthesis involves a base-catalyzed deprotection step, followed by an esterification reaction to form the target compound, with yields typically ranging from 70-85%.

(6-methoxycarbonyl-3-pyridyl)boronic acid is primarily used in the pharmaceutical industry for organic synthesis, particularly in the preparation of boronate esters and organoboron compounds. It also finds applications in the polymer industry for the synthesis of functional polymers and as a catalyst in various polymerization reactions.

When handling (6-methoxycarbonyl-3-pyridyl)boronic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbents, and the area should be thoroughly washed with water. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal procedures.