L-alpha-Aspartyl-N-(2,2,4,4-tetramethyl-3-thietanyl)-D-alaninamide hydrate (2:5)(CAS: 99016-42-9)

L-alpha-Aspartyl-N-(2,2,4,4-tetramethyl-3-thietanyl)-D-alaninamide hydrate (CAS: 99016-42-9) is a white crystalline solid with a molecular weight of approximately 474.5 g/mol. It has a high solubility in water and moderate solubility in ethanol. The compound is relatively stable under normal conditions but can degrade over time in the presence of moisture or heat. It is not reactive under standard laboratory conditions but may undergo hydrolysis in the presence of strong acids or bases.

L-alpha-Aspartyl-N-(2,2,4,4-tetramethyl-3-thietanyl)-D-alaninamide hydrate (CAS: 99016-42-9) is synthesized through a multi-step process involving the condensation of L-aspartic acid, 2,2,4,4-tetramethyl-3-thienylalanine, and D-alanine. The reaction typically proceeds under mild conditions using a catalytic amount of a suitable base like triethylamine. The product is purified by recrystallization from water, yielding a hydrate with a 2:5 ratio of the compound to water.

L-alpha-Aspartyl-N-(2,2,4,4-tetramethyl-3-thietanyl)-D-alaninamide hydrate (CAS: 99016-42-9) is primarily used in the pharmaceutical industry for the development of novel drugs. It also finds applications in the polymer industry as a monomer for the synthesis of biocompatible polymers. Additionally, it has potential uses in the semiconductor industry for the fabrication of electronic devices and in the sensing industry for the development of chemical sensors due to its unique chemical structure.

When handling L-alpha-Aspartyl-N-(2,2,4,4-tetramethyl-3-thietanyl)-D-alaninamide hydrate (CAS: 99016-42-9), it is important to wear appropriate personal protective equipment (PPE), such as gloves and safety goggles, and to ensure the process is carried out in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.