(3R,4R)-3-(3,4-Dihydroxybenzyl)-4-(3,4-dimethoxybenzyl)dihydro-2(3H)-furanone(CAS: 147022-95-5)

(3R,4R)-3-(3,4-Dihydroxybenzyl)-4-(3,4-dimethoxybenzyl)dihydro-2(3H)-furanone is a crystalline solid with a molecular weight of approximately 376.38 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. This compound is reactive towards electrophiles and can undergo nucleophilic substitution reactions. It is stable under normal conditions but should be stored in a dry, cool place to prevent degradation.

(3R,4R)-3-(3,4-Dihydroxybenzyl)-4-(3,4-dimethoxybenzyl)dihydro-2(3H)-furanone is typically synthesized by the condensation of 3,4-dimethoxybenzaldehyde and 3,4-dihydroxybenzyl alcohol using a controlled base catalyzed reaction. The yield is around 80%, and the product is isolated by recrystallization from ethanol. This process involves a mild and selective reaction under room temperature conditions.

(3R,4R)-3-(3,4-Dihydroxybenzyl)-4-(3,4-dimethoxybenzyl)dihydro-2(3H)-furanone is used in the pharmaceutical industry for the synthesis of bioactive compounds, as well as in the polymer industry for the development of functional polymers. It also finds applications in the sensor and semiconductor industries for its unique reactivity and stability.

When handling (3R,4R)-3-(3,4-Dihydroxybenzyl)-4-(3,4-dimethoxybenzyl)dihydro-2(3H)-furanone (CAS: 147022-95-5), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or a fume hood to prevent inhalation. In case of a spill, it should be immediately cleaned up using appropriate absorbent materials. Always consult the safety data sheet (SDS) for detailed handling and emergency procedures.