3,5-Dihydroxyphenyl Acetic Acid(CAS: 4670-09-1)

3,5-Dihydroxyphenyl Acetic Acid (DHPA, CAS: 4670-09-1) is a crystalline solid with a molecular weight of approximately 188.14 g/mol. It has a pKa of about 4.1 and is moderately soluble in water. Chemically, it is reactive with bases and oxidizing agents, making it susceptible to hydrolysis and oxidation.

3,5-Dihydroxyphenyl Acetic Acid is commonly synthesized via the condensation of vanillic acid with acetic anhydride in the presence of a catalyst like p-toluenesulfonic acid. This method provides a high yield of product and ensures good selectivity towards the desired dihydroxy derivative.

3,5-Dihydroxyphenyl Acetic Acid is predominantly used in the pharmaceutical industry for the synthesis of certain drugs, particularly those containing catechol structures. It also finds application in the production of sensors, as a precursor in the development of semiconductors, and as a component in some polymer formulations.

When handling 3,5-Dihydroxyphenyl Acetic Acid (CAS: 4670-09-1), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risk. Proper spill management procedures should be followed, and the Safety Data Sheet (SDS) should always be consulted for detailed information on handling and disposal.