2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-chromen-4-one(CAS: 4049-38-1)

2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-chromen-4-one is a yellow crystalline solid with a molecular weight of approximately 334.13 g/mol. It is slightly soluble in water and ethanol but more soluble in organic solvents. Its reactivity is moderate, showing good stability under normal conditions but can undergo hydrolysis in basic conditions. This compound is typically used in various applications requiring color stability and chemical inertness.

2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-chromen-4-one is commonly synthesized via the condensation of 2-hydroxyacetophenone with 3,4-dihydroxybenzaldehyde, followed by reduction and dehydrogenation steps. This synthesis often involves the use of a palladium catalyst and requires high selectivity and good yield, typically above 85%.

2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-chromen-4-one is widely used in the pharmaceutical industry for its antioxidant and anti-inflammatory properties. It is also employed in the polymer industry for its ability to enhance material properties. Additionally, it is used in sensor technologies for its optical and electrochemical characteristics, and in the semiconductor industry due to its stability and conductivity.

When handling 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-chromen-4-one, it is important to use personal protective equipment (PPE) including gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation. In case of skin contact, wash the affected area with soap and water. For spills, immediately clean up using appropriate absorbents and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.