4-{7-[6-Cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl}-2-fluorobenzoic acid(CAS: 1332391-04-4)

4-{7-[6-Cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl}-2-fluorobenzoic acid is a white solid with a molecular weight of approximately 530.53 g/mol. It is slightly soluble in water and ethanol, and more soluble in organic solvents like DMSO. This compound shows excellent stability under normal conditions but reacts with bases to form anionic derivatives. It is generally non-flammable and non-explosive.

4-{7-[6-Cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl}-2-fluorobenzoic acid is synthesized via a multi-step process involving aziridination, alkylation, and subsequent amidation reactions. Common catalysts include triphenylphosphine and sodium hydride. The yield is typically around 70%, with high selectivity towards the desired product.

4-{7-[6-Cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl}-2-fluorobenzoic acid is primarily used in the pharmaceutical industry due to its potential as an intermediate in the synthesis of bioactive compounds and anti-inflammatory drugs. It is also studied for its application in sensor technology and as a building block in organic synthesis.

When handling 4-{7-[6-Cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl}-2-fluorobenzoic acid (CAS: 1332391-04-4), use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store the compound in a cool, dry place away from heat sources and incompatible materials. Use a fume hood during handling and disposal. Always refer to the safety data sheet (SDS) for detailed safety information.