1-(Bromomethyl)-2,3-difluorobenzene(CAS: 113211-94-2)

1-(Bromomethyl)-2,3-difluorobenzene (CAS: 113211-94-2) is a crystalline solid with a molecular weight of approximately 215.01 g/mol. It has a low solubility in water but is more soluble in organic solvents like dichloromethane and chloroform. Chemically, it is less reactive towards nucleophiles due to the presence of the bromomethyl group. It is stable under normal conditions but can undergo halogenation reactions under certain conditions.

1-(Bromomethyl)-2,3-difluorobenzene (CAS: 113211-94-2) can be synthesized via a one-pot reaction where 2,3-difluorobenzyl bromide reacts with 1-bromopropane in the presence of a base such as potassium carbonate. This method provides a high yield and good selectivity for the desired product under mild conditions.

1-(Bromomethyl)-2,3-difluorobenzene (CAS: 113211-94-2) is used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry to modify the properties of polymers, in the semiconductor industry for organic semiconductor materials, and in sensor technology for its chemical reactivity.

When handling 1-(Bromomethyl)-2,3-difluorobenzene (CAS: 113211-94-2), it is crucial to wear appropriate personal protective equipment (PPE), such as gloves, safety goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. In case of a spill, use appropriate spill cleanup materials and ensure proper disposal. Always refer to the safety data sheet (SDS) for detailed emergency procedures and storage recommendations.