4-Nitro-1H-pyrazol-3-amine(CAS: 16115-82-5)

4-Nitro-1H-pyrazol-3-amine is a crystalline solid with a molecular weight of approximately 174.08 g/mol. It is slightly soluble in water and ethanol. The compound is reactive due to the presence of a nitro group and an amine group, making it suitable for various chemical transformations. It is also slightly basic due to the amine functionality.

4-Nitro-1H-pyrazol-3-amine can be synthesized via the nitration of 1H-pyrazol-3-amine followed by reduction of the nitro group. Commonly, the nitration is performed using nitric acid in the presence of sulfuric acid as a catalyst. The reduction step is often carried out using hydrogen gas over a catalyst like palladium on carbon.

4-Nitro-1H-pyrazol-3-amine is used in the pharmaceutical industry for the synthesis of certain medicinal compounds. It is also explored in the polymer industry for functionalizing polymers and in the semiconductor industry for use as a dopant material in certain applications.

When handling 4-Nitro-1H-pyrazol-3-amine, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood due to its volatility and reactivity. Spills should be cleaned up immediately with appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal guidelines.