(3R)-3-Ethoxy-2-methylnonane(CAS: 78330-20-8)

(3R)-3-Ethoxy-2-methylnonane is a colorless liquid with a distinct odor. It has a molecular weight of approximately 174.25 g/mol and a boiling point around 165°C. The compound is moderately soluble in water but soluble in common organic solvents such as ethanol and acetone. It is less reactive than more substituted nonanes, showing low reactivity towards common chemical reagents.

(3R)-3-Ethoxy-2-methylnonane can be synthesized via a stereoselective reduction of 3-ethoxynonan-2-one using a chiral catalyst such as BINAP-Ruthenium complex. The reaction typically provides good yield and selectivity, with the (3R) stereoisomer being the major product. The method involves mild conditions and is suitable for preparative scale synthesis.

(3R)-3-Ethoxy-2-methylnonane is primarily used in the fragrance and flavor industry due to its pleasant aroma. It is also employed in the pharmaceutical industry as a synthetic intermediate. Additionally, it finds applications in the production of certain polymers and as a solvent in analytical chemistry. Its specific use in semiconductors and sensors is limited due to its volatility and reactivity.

When handling (3R)-3-Ethoxy-2-methylnonane, appropriate personal protective equipment (PPE) including gloves, goggles, and lab coat should be worn. The compound should be managed in a well-ventilated area or fume hood due to its volatile nature. Spills should be cleaned up with absorbent material and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.