6-Bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-[(3S)-3-piperidinyl]pyrazolo[1,5-a]pyrimidin-7-amine(CAS: 891494-64-7)

6-Bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-[(3S)-3-piperidinyl]pyrazolo[1,5-a]pyrimidin-7-amine is a crystalline solid with a molecular weight of approximately 432.12 g/mol. It has a solubility of about 10 mg/L in water. This compound is moderately reactive, showing limited reactivity with common organic and inorganic acids and bases. It is soluble in common organic solvents such as dimethylformamide (DMF) and acetonitrile.

6-Bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-[(3S)-3-piperidinyl]pyrazolo[1,5-a]pyrimidin-7-amine is typically synthesized through multistep organic synthesis involving bromination, condensation, and ring formation reactions. Commonly used catalysts include palladium complexes or other transition metal catalysts. The overall yield is approximately 60-70%.

6-Bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-[(3S)-3-piperidinyl]pyrazolo[1,5-a]pyrimidin-7-amine is primarily used in the pharmaceutical industry due to its potential as a drug candidate. It may also have applications in polymer manufacturing and sensor technology due to its chemical structure and reactivity.

When handling 6-Bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-[(3S)-3-piperidinyl]pyrazolo[1,5-a]pyrimidin-7-amine, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. This compound should be handled in a fume hood due to its potential volatility. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.