2-(2-Fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(CAS: 876062-39-4)

2-(2-Fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 876062-39-4) is a colorless or white crystalline solid. It has a molecular weight of approximately 260.22 g/mol. This compound is sparingly soluble in water but highly soluble in organic solvents like dichloromethane and toluene. It is known for its reactivity, particularly in boron-containing reactions, and its stability under neutral and basic conditions.

2-(2-Fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 876062-39-4) is synthesized using a variety of methods, including the Stille coupling reaction. This involves the reaction of a fluoroaryl bromide with di-tert-butyl cuprate and tetraethylborate in a suitable solvent. The reaction typically requires a catalyst and generates good yields, with high selectivity for the desired product.

2-(2-Fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 876062-39-4) finds application in several industries, particularly in pharmaceuticals for drug synthesis, and in the polymer industry for the development of novel materials. It is also used in sensor technology and semiconductor manufacturing for specific functionalization and purification steps.

When handling 2-(2-Fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 876062-39-4), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood. In the event of a spill, it should be cleaned up using appropriate absorbent materials. Always refer to the safety data sheet (SDS) for detailed handling and disposal instructions.