(2-Methyl-1-naphthyl)boronic acid(CAS: 103989-84-0)

(2-Methyl-1-naphthyl)boronic acid is a white crystalline solid with a molecular weight of approximately 266.31 g/mol. It has a solubility of about 0.7 g/100 mL in water and is slightly soluble in ethanol. Chemically, it shows reactivity typical of boronic acids, undergoing Suzuki-Miyaura coupling reactions with aryl halides in the presence of palladium catalysts.

(2-Methyl-1-naphthyl)boronic acid is typically synthesized via a Stille coupling reaction, where 2-methyl-1-naphthyl bromide reacts with boron tribromide in the presence of a palladium catalyst. This method provides good yield and selectivity for the boronic acid product.

(2-Methyl-1-naphthyl)boronic acid is used in the pharmaceutical industry for the synthesis of drug intermediates, in the polymer industry for the production of functionalized polymers, and in semiconductor manufacturing for the fabrication of electronic materials. It also finds applications in sensor technology.

When handling (2-Methyl-1-naphthyl)boronic acid, it is important to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. For detailed safety information, refer to the Material Safety Data Sheet (MSDS/SDS).