Pyrido[3,2-d]pyrimidin-4(1H)-one(CAS: 37538-67-3)

Pyrido[3,2-d]pyrimidin-4(1H)-one is a white crystalline solid with a molecular weight of approximately 165.15 g/mol. It is slightly soluble in water but more soluble in organic solvents like methanol and ethanol. This compound is chemically stable but can react with strong acids or bases to form other pyrimidine derivatives.

Pyrido[3,2-d]pyrimidin-4(1H)-one can be synthesized through the condensation of 2,4-dichloropyrimidine with 1,3-diaminopropane followed by hydrolysis. This process involves the use of a catalyst and typically yields a high percentage of the target compound with good selectivity.

Pyrido[3,2-d]pyrimidin-4(1H)-one is used in the pharmaceutical industry for its potential as a drug candidate, particularly in the treatment of certain diseases. It is also utilized in the chemical industry for its reactivity and in the production of other chemical intermediates.

Pyrido[3,2-d]pyrimidin-4(1H)-one should be handled using appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be stored in a cool, dry place and away from direct sunlight. Spills should be cleaned up using appropriate methods as outlined in the safety data sheet (SDS). Handling should always be done in a well-ventilated area or a fume hood.