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N-(3-Chloro-4-fluorophenyl)-6-(3-chloropropoxy)-7-methoxyquinazolin-4-amine(CAS: 912556-91-3)

N-(3-Chloro-4-fluorophenyl)-6-(3-chloropropoxy)-7-methoxyquinazolin-4-amine
CAS Number

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Basic Information

Molecular Formula
C18H16Cl2FN3O2
Molecular Weight
396.25 g/mol

Chemical Identifiers

SMILES
COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCCl
InChIKey
LYHIGZLXZKJTPS-UHFFFAOYSA-N

Database References

MDL Number
MFCD26383919

FAQ

This compound is a crystalline solid with a molecular weight of approximately 415.18 g/mol. It is slightly soluble in water and organic solvents. The compound is known for its reactivity towards nucleophiles and electrophiles, showing some basic properties due to the amine functional group.
This compound can be synthesized via a multistep process involving the protection of a phenolic hydroxyl group, followed by introduction of a chloroalkoxy group, and subsequent quinazolinone formation. The key reagents include chloroalkyl halides and amines, with a yield of around 70-80%. Detailed synthesis protocols can be found in relevant chemical journals.
This compound is primarily used in the pharmaceutical industry due to its potential anti-inflammatory and anti-cancer properties. It may also find applications in the development of advanced materials and sensors, although its specific uses in these fields are limited.
When handling this compound, it is recommended to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up carefully, and the material safety data sheet (MSDS) should always be consulted for specific handling instructions.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

Contact Information

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