Cyclobutanecarbonyl chloride(CAS: 5006-22-4)

Cyclobutanecarbonyl chloride is a colorless to light yellow liquid with a molecular weight of approximately 96.07 g/mol. It has a melting point of -80°C and a boiling point of 67-68°C. Solubility in water is low, and it is soluble in ethanol, ether, and acetone. It is highly reactive due to the presence of the acyl chloride functional group.

Cyclobutanecarbonyl chloride can be synthesized via the reaction of cyclobutanone with thionyl chloride. The process yields the desired product with good selectivity and a moderate yield. The reaction can be carried out under mild conditions, and the use of a catalyst may enhance the reaction rate and product purity.

Cyclobutanecarbonyl chloride is primarily used in the synthesis of pharmaceuticals, as an intermediate in the production of polymers, and in the development of sensors. It also finds application in the manufacturing of semiconductors and other advanced materials due to its unique chemical properties.

When handling cyclobutanecarbonyl chloride, proper personal protective equipment (PPE) is essential, including safety goggles, gloves, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be handled by professional personnel using appropriate safety measures. Consult the Safety Data Sheet (SDS) for detailed instructions on handling and disposal.