Ethyl 3-[(1R)-1-phenylethyl]-2-thioxo-2,3-dihydro-1H-imidazole-4-carboxylate(CAS: 84711-26-2)

Ethyl 3-[(1R)-1-phenylethyl]-2-thioxo-2,3-dihydro-1H-imidazole-4-carboxylate is a crystalline compound with a molecular weight of approximately 302.34 g/mol. It has a low solubility in water but is soluble in organic solvents. The compound exhibits moderate reactivity towards nucleophiles and is stable under normal storage conditions. It can be stored at room temperature away from direct sunlight and moisture.

Ethyl 3-[(1R)-1-phenylethyl]-2-thioxo-2,3-dihydro-1H-imidazole-4-carboxylate can be synthesized via a multistep process involving the formation of a thioimidazole intermediate, followed by alkylation with ethyl bromide. The reaction typically involves the use of a Lewis acid catalyst and is carried out under mild conditions. The yield of the final product is around 75-80%, depending on the purity of starting materials and reaction conditions.

Ethyl 3-[(1R)-1-phenylethyl]-2-thioxo-2,3-dihydro-1H-imidazole-4-carboxylate is primarily used in the pharmaceutical industry for its bioactive properties. It is also explored in the development of new materials, particularly in the area of sensors and semiconductors. Its potential applications in polymer chemistry and as a reagent in organic synthesis are also being investigated.

When handling Ethyl 3-[(1R)-1-phenylethyl]-2-thioxo-2,3-dihydro-1H-imidazole-4-carboxylate, it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Ensure the use of a fume hood during operations to minimize inhalation risks. In case of spills, immediately clean up using absorbent material and dispose of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.