2-[(E)-(Phenylimino)methyl]phenol(CAS: 779-84-0)

2-[(E)-(Phenylimino)methyl]phenol (CAS: 779-84-0) is a colorless to white crystalline solid with a molecular weight of approximately 240.21 g/mol. It has a pKa of about 12.2 and is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. This compound is relatively stable under normal conditions but can react with strong acids and bases. It is also known to undergo photodegradation under UV light.

2-[(E)-(Phenylimino)methyl]phenol (CAS: 779-84-0) is commonly synthesized via the condensation of phenylacetaldehyde with phenylhydrazine. The reaction typically proceeds under acidic conditions, with hydrochloric acid serving as a catalyst. The yield is around 70-80% with good selectivity for the E-isomer.

2-[(E)-(Phenylimino)methyl]phenol (CAS: 779-84-0) is used in the pharmaceutical industry as a precursor for the synthesis of certain anti-inflammatory and antipyretic drugs. It also finds applications in the polymer industry for the modification of polymer properties and in the electronics industry for the production of semiconductor materials and sensors.

When handling 2-[(E)-(Phenylimino)methyl]phenol (CAS: 779-84-0), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a fume hood to minimize inhalation risk. Spills should be cleaned up immediately using appropriate absorbents, and the area should be well-ventilated. A Safety Data Sheet (SDS) should be consulted for detailed handling and emergency procedures.