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[3-Methoxy-5-(trifluoromethyl)phenyl]boronic acid(CAS: 871332-97-7)

[3-Methoxy-5-(trifluoromethyl)phenyl]boronic acid
CAS Number

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Basic Information

Molecular Formula
C8H8BF3O3
Molecular Weight
219.95 g/mol

Physical Properties

Melting Point
159-162
Boiling Point
318.3℃ at 760 mmHg
Density
1.36
Flash Point
146.3°C
Water Solubility
Sparingly soluble in water 0.42 g/L @ 25°C.

Chemical Identifiers

SMILES
COc1cc(cc(c1)C(F)(F)F)B(O)O
InChIKey
GKEMDZIGTOAZRK-UHFFFAOYSA-N

Database References

MDL Number
MFCD08056362

FAQ

[3-Methoxy-5-(trifluoromethyl)phenyl]boronic acid (CAS: 871332-97-7) is a white crystalline solid with a molecular weight of approximately 303.13 g/mol. It has a low solubility in water but is more soluble in organic solvents. It is a reactive compound, especially in the presence of bases or reducing agents. This compound exhibits good stability under normal storage conditions but should be handled with care due to its reactivity.
[3-Methoxy-5-(trifluoromethyl)phenyl]boronic acid (CAS: 871332-97-7) is usually synthesized via the Suzuki coupling reaction. This involves the reaction of 3-methoxy-5-(trifluoromethyl)phenyllithium with boronic acid in the presence of a palladium catalyst and a base. The reaction is typically carried out in an organic solvent at room temperature, with high selectivity and yield.
[3-Methoxy-5-(trifluoromethyl)phenyl]boronic acid (CAS: 871332-97-7) finds applications in various industries, including pharmaceuticals for organic synthesis, polymers for functional materials, and sensors for detecting specific chemicals. It is also used in the semiconductor industry for etching and patterning processes.
When handling [3-Methoxy-5-(trifluoromethyl)phenyl]boronic acid (CAS: 871332-97-7), it is important to use personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbents, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

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