(1R,3R)-3-Aminocyclopentanecarboxylic acid(CAS: 71869-43-7)

(1R,3R)-3-Aminocyclopentanecarboxylic acid is a white crystalline powder with a molecular weight of approximately 135.16 g/mol. It has a pKa of about 4.5 and is soluble in water (10 g/L). It is moderately reactive and can form salts with acids. Common solvents include ethanol and methanol.

(1R,3R)-3-Aminocyclopentanecarboxylic acid can be synthesized via the Strecker synthesis, where an aldehyde, ammonia, and hydrogen cyanide react under catalytic conditions. Alternatively, it can be derived from (1R,3R)-3-aminocyclopentanol through acylation reactions. Yield and selectivity are good, typically around 85%-95%.

(1R,3R)-3-Aminocyclopentanecarboxylic acid is used in the pharmaceutical industry for the synthesis of certain drug molecules. It also finds application in polymers, where it serves as a monomer or a modifier. Additionally, it is used in the development of sensors and as a precursor in semiconductor manufacturing processes.

When handling (1R,3R)-3-Aminocyclopentanecarboxylic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a laboratory coat. Work in a well-ventilated area or fume hood to minimize inhalation risks. Store the compound in a cool, dry place away from direct sunlight. In case of spill, follow standard laboratory safety procedures and refer to the Safety Data Sheet (SDS) for detailed instructions.