6-Hydroxy-2-hexanone(CAS: 21856-89-3)

6-Hydroxy-2-hexanone (CAS: 21856-89-3) is a clear, colorless liquid with a molecular weight of 110.14 g/mol. It has a low viscosity and a fruity odor. The compound is miscible with water and ethanol. It is slightly soluble in nonpolar solvents. It is reactive towards bases and can undergo hydrolysis under basic conditions. It is used in organic synthesis due to its reactivity and ease of manipulation.

6-Hydroxy-2-hexanone can be synthesized by the reduction of 2-hexanone with sodium borohydride or a similar reducing agent. Another method involves the condensation of acetaldehyde and acetic anhydride followed by hydrolysis. This compound can also be prepared by the oxidation of 2-hexanol or the reduction of 6-nitro-2-hexanone. These processes yield good yields and controlled selectivity.

6-Hydroxy-2-hexanone (CAS: 21856-89-3) is primarily used in the pharmaceutical industry for the synthesis of various drugs, as well as in the polymer industry for the production of certain polymers. It is also utilized in the synthesis of fragrances and flavorings, and in the production of sensors and semiconductors due to its reactivity and volatility.

When handling 6-Hydroxy-2-hexanone (CAS: 21856-89-3), it is important to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood due to its volatility. Spills should be cleaned up with caution, using appropriate spill kits, and the area should be ventilated thoroughly. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.