N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-2'-fluorocytidine(CAS: 159414-98-9)

N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-2'-fluorocytidine is a crystalline compound with a molecular weight of approximately 722.5 g/mol. It is poorly soluble in water but has good solubility in organic solvents like dimethyl sulfoxide (DMSO). This compound is reactive and susceptible to hydrolysis under basic conditions. It can form hydrogen bonds and exhibit fluorescence under certain conditions.

N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-2'-fluorocytidine can be synthesized via a multi-step process involving acetylation, coupling, and protection/deprotection steps. Commonly used solvents include dichloromethane and N,N-dimethylformamide (DMF). The reaction typically requires a catalyst such as triphenylphosphine and is achieved with high yield and good selectivity.

This compound is primarily used in the pharmaceutical industry for its potential as a drug candidate. It can also be applied in the development of fluorescent probes for biological imaging and as a component in some specialized chemical sensors.

When handling N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-2'-fluorocytidine, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store the compound in a cool, well-ventilated area, away from direct sunlight. Spills should be cleaned up using appropriate absorbent materials, and the area should be flushed with water. Always refer to the Material Safety Data Sheet (MSDS) for detailed handling instructions and emergency procedures.