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6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole(CAS: 642494-36-8)

6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
CAS Number

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Basic Information

Molecular Formula
C14H18BNO2
Molecular Weight
243.12 g/mol

Physical Properties

Boiling Point
396°C at 760 mmHg

Chemical Identifiers

SMILES
B1(OC(C(O1)(C)C)(C)C)C2=CC3=C(C=C2)C=CN3
InChIKey
VNDFXJNIKZCQRY-UHFFFAOYSA-N

Database References

MDL Number
MFCD07368852

FAQ

The compound 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS: 642494-36-8) falls under the jurisdiction of various regulations including the REACH system for chemicals in the EU, the Globally Harmonized System of Classification and Labeling of Chemicals (GHS) for occupational safety and health, and may require registration with the U.S. Environmental Protection Agency (EPA) if it is used in commercial products. Compliance with these guidelines is essential for manufacturing, distribution, and use.
Alternatives to 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS: 642494-36-8) in synthesis include various boronic acid derivatives such as pinacol boronate or 2-bromopyridine borane. These can serve as precursors in similar reactions, providing comparable reactivity for Suzuki coupling and other cross-coupling reactions.
The market for 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS: 642494-36-8) is driven by its use in pharmaceutical and material sciences. Research trends focus on its application in drug discovery, particularly in the development of new anti-cancer and anti-inflammatory agents. Additionally, its use in the synthesis of complex organic molecules is growing due to its reactivity in cross-coupling reactions.
Waste containing 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS: 642494-36-8) should be collected in appropriate containers and disposed of through professional waste disposal services. Incineration or chemical treatment may be necessary to ensure complete decomposition, and environmental protection measures should be followed to prevent contamination of soil and water. Compliance with local hazardous waste regulations is essential.

Safety Notice

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