2-Bromo-1-iodo-3-methoxybenzene(CAS: 74128-84-0)

CAS Number
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Basic Information
Molecular Formula
C7H6BrIO
Molecular Weight
312.93 g/mol
Physical Properties
Melting Point
46-47 ºC (ethanol )
Density
2.062±0.06 g/cm3 (20 ºC 760 Torr),
Chemical Identifiers
SMILES
COC1=C(C(=CC=C1)I)Br
InChIKey
BBVDXMFOLMWGNB-UHFFFAOYSA-N
Database References
MDL Number
MFCD18391616
FAQ
2-Bromo-1-iodo-3-methoxybenzene (CAS: 74128-84-0) is a solid with a crystalline form. The molecular weight is approximately 325.04 g/mol. It is slightly soluble in water but miscible with organic solvents like ethanol and acetone. Chemically, it is highly reactive due to the presence of bromine and iodine substituents, making it a versatile reagent in organic synthesis.
2-Bromo-1-iodo-3-methoxybenzene (CAS: 74128-84-0) is typically synthesized via aromatic bromination and iodination of 3-methoxybenzene. Commonly, the bromination is performed using N-bromosuccinimide (NBS) in the presence of a radical initiator. Subsequently, the brominated product is iodinated using N-iodosuccinimide (NIS) under appropriate conditions to yield the final compound.
2-Bromo-1-iodo-3-methoxybenzene (CAS: 74128-84-0) is used in the pharmaceutical industry for the synthesis of certain drugs, as a precursor in polymer chemistry for the development of advanced materials, and in the production of sensors and semiconductors due to its unique reactivity and chemical properties.
When handling 2-Bromo-1-iodo-3-methoxybenzene (CAS: 74128-84-0), it is essential to follow strict safety protocols. Wear appropriate personal protective equipment (PPE), including gloves, lab coat, and safety goggles. Work in a well-ventilated area or a fume hood to minimize exposure. Store the compound in a dry, cool place away from direct sunlight. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
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