ethyl 5-hydroxy-2-methyl-1H-indole-3-carboxylate(CAS: 7598-91-6)

Ethyl 5-hydroxy-2-methyl-1H-indole-3-carboxylate (CAS: 7598-91-6) is a crystalline compound with a molecular weight of approximately 224.24 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. This compound exhibits moderate reactivity, with potential for ester hydrolysis under acidic conditions. It is stable under normal conditions but should be stored in a cool, dry place away from moisture and heat.

Ethyl 5-hydroxy-2-methyl-1H-indole-3-carboxylate (CAS: 7598-91-6) is synthesized via a multi-step process involving the formation of an indole ring followed by esterification. Commonly, this involves the reaction of 2-methyl-1H-indole with acetyl chloride in the presence of a base like pyridine, followed by the addition of an alcohol to form the ester. This method yields a relatively pure product with high selectivity and good yield.

Ethyl 5-hydroxy-2-methyl-1H-indole-3-carboxylate (CAS: 7598-91-6) finds applications in the pharmaceutical industry, where it is used as an intermediate in the synthesis of certain drugs. It is also utilized in the production of polymers, sensors, and semiconductors for its unique chemical structure and reactivity.

When handling ethyl 5-hydroxy-2-methyl-1H-indole-3-carboxylate (CAS: 7598-91-6), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood due to its potential for vapor release. In case of a spill, it should be cleaned up using absorbent materials and disposed of according to local regulations. Always consult the safety data sheet (SDS) for detailed handling instructions and emergency procedures.