3-Bromodihydro-2H-pyran-4(3H)-one(CAS: 98021-79-5)

3-Bromodihydro-2H-pyran-4(3H)-one is a crystalline solid with a molecular weight of approximately 222.01 g/mol. It has a low solubility in water but is more soluble in common organic solvents like ethanol and acetone. This compound is known for its chemical reactivity, particularly its tendency to undergo nucleophilic substitution reactions due to the presence of the bromine atom.

3-Bromodihydro-2H-pyran-4(3H)-one is typically synthesized via a bromination reaction of 3-hydroxy-2H-pyran-4(3H)-one. The reaction is usually catalyzed by N-bromosuccinimide (NBS) in the presence of a radical initiator like benzoyl peroxide. The yield and selectivity of the reaction can be improved by optimizing reaction conditions such as temperature and solvent choice.

3-Bromodihydro-2H-pyran-4(3H)-one is primarily used in the pharmaceutical industry for the synthesis of various medicinal compounds. It also finds applications in the polymer industry for modifying the properties of polymers, and in the sensor and semiconductor industries for specific chemical detection and electronic applications.

When handling 3-Bromodihydro-2H-pyran-4(3H)-one, it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. The compound should be handled in a fume hood due to its potential volatility and reactivity. In case of spill, it should be cleaned up carefully according to the Safety Data Sheet (SDS) guidelines. Always refer to the latest SDS for detailed safety information.