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N-({2-[4-(2-Ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]ethyl}carbamoyl)-4-methylbenzenesulfonamide(CAS: 415903-37-6)

N-({2-[4-(2-Ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]ethyl}carbamoyl)-4-methylbenzenesulfonamide
CAS Number

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Basic Information

Molecular Formula
C26H29N5O3S
Molecular Weight
491.62 g/mol

Physical Properties

Melting Point
>136 ºC (Grapiprant hydrochloride)

Chemical Identifiers

SMILES
CCc1nc2c(nc(cc2n1c3ccc(cc3)CCNC(=O)NS(=O)(=O)c4ccc(cc4)C)C)C
InChIKey
HZVLFTCYCLXTGV-UHFFFAOYSA-N

Database References

MDL Number
MFCD16628076

FAQ

N-({2-[4-(2-Ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]ethyl}carbamoyl)-4-methylbenzenesulfonamide (CAS: 415903-37-6) is a crystalline solid with a molecular weight of approximately 535.43 g/mol. It has a low solubility in water but is soluble in organic solvents like DMSO and methanol. The compound shows good reactivity towards nucleophiles and can undergo substitution reactions. It has a pKa of around 8.5, indicating basicity.
N-({2-[4-(2-Ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]ethyl}carbamoyl)-4-methylbenzenesulfonamide (CAS: 415903-37-6) is synthesized through multi-step reactions involving condensation, substitution, and sulfonamide formation. The key steps include the preparation of the imidazo[4,5-c]pyridin-1-yl moiety, coupling with the phenethyl carbamoyl group, and final sulfonamide formation. The reaction requires careful control of conditions to achieve high yield and selectivity.
N-({2-[4-(2-Ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]ethyl}carbamoyl)-4-methylbenzenesulfonamide (CAS: 415903-37-6) is primarily used in the pharmaceutical industry for its potential as an antifungal agent. It may also have applications in sensor technology and as a component in certain drug delivery systems. Research is ongoing to explore its use in other areas.
When handling N-({2-[4-(2-Ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]ethyl}carbamoyl)-4-methylbenzenesulfonamide (CAS: 415903-37-6), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, lab coat, and safety glasses. Storage should be in a dry, cool place, away from direct sunlight and heat sources. In case of spills, handle with caution and follow proper laboratory safety guidelines. Always refer to the Safety Data Sheet (SDS) for detailed safety information.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

Contact Information

Contact Person

Manager Chen

Email

dshs21@eagle-pharm.com