4-[(E)-2-(4-Carbamimidoylphenyl)vinyl]-3-hydroxybenzenecarboximidamide methanesulfonate (1:2)(CAS: 223769-64-0)

4-[(E)-2-(4-Carbamimidoylphenyl)vinyl]-3-hydroxybenzenecarboximidamide methanesulfonate (CAS: 223769-64-0) is a white crystalline solid with a molecular weight of approximately 468.56 g/mol. It has a pKa of about 7.5 and is moderately soluble in water and polar organic solvents. This compound is known for its reactivity, particularly its ability to undergo nucleophilic substitution reactions and condensation reactions.

4-[(E)-2-(4-Carbamimidoylphenyl)vinyl]-3-hydroxybenzenecarboximidamide methanesulfonate is typically synthesized through a multi-step process involving the coupling of 4-carbamimidoylphenyl vinyl ketone with 3-hydroxybenzene-1-carboxylic acid methanesulfonate. The synthesis involves protecting groups and careful control of reaction conditions to achieve high selectivity and yield. Common catalysts include metal complexes and organocatalysts.

4-[(E)-2-(4-Carbamimidoylphenyl)vinyl]-3-hydroxybenzenecarboximidamide methanesulfonate finds application in the pharmaceutical industry for its potential as a therapeutic agent. It is also used in the polymer industry for the modification of polymer properties. Additionally, it has emerging uses in sensor technology and semiconductor manufacturing for its reactivity and stability.

When handling 4-[(E)-2-(4-Carbamimidoylphenyl)vinyl]-3-hydroxybenzenecarboximidamide methanesulfonate (CAS: 223769-64-0), it is essential to wear appropriate personal protective equipment (PPE), such as gloves, goggles, and lab coats. Work should be carried out in a well-ventilated area or a fume hood. Spills should be handled with caution using appropriate absorbent materials, and the material safety data sheet (MSDS) should be consulted for detailed spill cleanup procedures.