Ethyl 2-isothiocyanatobenzoate(CAS: 99960-09-5)

Ethyl 2-isothiocyanatobenzoate (CAS: 99960-09-5) is a white crystalline solid with a molecular weight of approximately 224.24 g/mol. It has limited water solubility but is more soluble in organic solvents like acetone and ethanol. It is relatively stable but can react with strong reducing agents. It sublimates easily and has a pungent odor similar to other isothiocyanate derivatives.

Ethyl 2-isothiocyanatobenzoate (CAS: 99960-09-5) is typically synthesized by the reaction of benzoic acid with ethyl isothiocyanate in the presence of a catalytic amount of an acid like sulfuric acid. The reaction proceeds through nucleophilic substitution, yielding the target compound with high yield and good selectivity.

Ethyl 2-isothiocyanatobenzoate (CAS: 99960-09-5) finds applications in various industries, particularly in the pharmaceutical sector for synthesis of biologically active compounds, in the polymer industry as a stabilizer, and in the semiconductor industry for surface modification. It also has potential in sensors and as a reagent for analytical chemistry.

Proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn when handling Ethyl 2-isothiocyanatobenzoate (CAS: 99960-09-5). It should be handled in a well-ventilated area or a fume hood due to its pungent odor and potential for inhalation hazards. Spills should be cleaned up using appropriate safety measures, and an SDS (Safety Data Sheet) should be consulted for detailed handling procedures and emergency response guidelines.