5-Bromo-2-methyl-3-pyridinamine(CAS: 914358-73-9)

5-Bromo-2-methyl-3-pyridinamine is a crystalline solid with a molecular weight of approximately 193.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and DMSO. The compound is moderately reactive, particularly in the presence of strong bases or reducing agents. It is stable under normal storage conditions but undergoes hydrolysis under acidic conditions.

5-Bromo-2-methyl-3-pyridinamine is typically synthesized via a mild bromination of 2-methyl-3-pyridinamine using N-bromosuccinimide (NBS) in an inert solvent like dichloromethane. The reaction proceeds at room temperature with high selectivity and yield, making it a straightforward procedure.

5-Bromo-2-methyl-3-pyridinamine is used in the pharmaceutical industry for the synthesis of certain medicinal compounds. It also finds applications in the development of sensors and semiconductors due to its unique chemical properties and stability.

Proper handling of 5-Bromo-2-methyl-3-pyridinamine requires the use of personal protective equipment (PPE) including gloves, goggles, and a lab coat. Storage should be in a dry, cool place away from direct sunlight. In case of spills, clean up with appropriate absorbents and follow safety data sheet (SDS) guidelines for disposal. Always work in a well-ventilated area or fume hood due to its potential reactivity.