1-Bromo-5-fluoropentane(CAS: 407-97-6)

1-Bromo-5-fluoropentane (CAS: 407-97-6) is a colorless liquid with a molecular weight of approximately 158.01 g/mol. It has a boiling point of 134-135°C and a melting point of -28°C. The compound is slightly soluble in water but miscible with common organic solvents. It is moderately reactive, especially with nucleophiles and reducing agents.

1-Bromo-5-fluoropentane (CAS: 407-97-6) can be synthesized by the reaction of 5-fluoropentan-1-ol with bromine in the presence of a Lewis acid catalyst, such as aluminum tribromide. This method provides good yield and high selectivity. Other methods include radical bromination of 5-fluoropentan-1-ol using peroxides as initiators.

1-Bromo-5-fluoropentane (CAS: 407-97-6) is primarily used in the pharmaceutical industry for the synthesis of various fluorinated compounds, including drugs. It is also utilized in the polymer industry for the production of fluorinated polymers with specific properties. Additionally, it can be applied in the semiconductor industry for the fabrication of microelectronic devices.

When handling 1-Bromo-5-fluoropentane (CAS: 407-97-6), it is essential to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a well-ventilated area, preferably under a fume hood. Spills should be cleaned up using appropriate absorbents, and the area should be thoroughly cleaned with water. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.