2-(Acetoxymethoxy)-1,3-propanediyl diacetate(CAS: 86357-13-3)

2-(Acetoxymethoxy)-1,3-propanediyl diacetate is a colorless to slightly yellowish crystalline solid with a molecular weight of approximately 230.27 g/mol. It has a melting point of 60-62°C and is soluble in common organic solvents such as ethanol, acetone, and dichloromethane. The compound is relatively stable under normal conditions but can react with strong bases to form ester derivatives. It exhibits low reactivity towards nucleophiles and electrophiles under mild conditions.

2-(Acetoxymethoxy)-1,3-propanediyl diacetate can be synthesized via the esterification of 1,3-propanediol with acetic anhydride in the presence of a catalyst such as pyridine. The reaction is typically carried out at room temperature under anhydrous conditions to achieve a high yield. The process is selective and efficient, with a good overall yield of around 90%.

2-(Acetoxymethoxy)-1,3-propanediyl diacetate finds applications in various industries. It is used in the pharmaceutical sector for the synthesis of certain intermediates. In the polymer industry, it serves as a monomer or a cross-linking agent. It also has applications in sensor technology, where it can be used as a recognition element, and in semiconductor manufacturing as a component in resist materials.

When handling 2-(Acetoxymethoxy)-1,3-propanediyl diacetate, it is important to use proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or in a fume hood. In case of a spill, it should be contained and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.