2-Methyl-2-propanyl (1R,5S,6r)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate(CAS: 419572-18-2)

2-Methyl-2-propanyl (1R,5S,6r)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate is a crystalline compound with a molecular weight of approximately 238.32 g/mol. It has a low solubility in water but is soluble in organic solvents like methanol and ethanol. This compound exhibits reactivity typical of esters and azabicycles, making it susceptible to hydrolysis under basic conditions and prone to nucleophilic substitution reactions.

2-Methyl-2-propanyl (1R,5S,6r)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate is synthesized through a multi-step process involving the condensation of a specific aldehyde with an amine, followed by an intramolecular cyclization reaction. The synthesis typically requires the use of a Lewis acid catalyst and involves high selectivity and moderate yield.

2-Methyl-2-propanyl (1R,5S,6r)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate is primarily used in pharmaceuticals for its potential in drug discovery and development. It also finds applications in the synthesis of certain polymers and in sensor technology for its chemical reactivity.

When handling 2-Methyl-2-propanyl (1R,5S,6r)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be used in a well-ventilated area, preferably a fume hood, to minimize inhalation risk. Spills should be cleaned up with caution, using appropriate absorbents, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.