(2R,3R)-3,5,7-Trihydroxy-2-[(2R,3S)-7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-1-benzofuran-5-yl]-2,3-dihydro-4H-chromen-4-one(CAS: 33889-69-9)

The compound (2R,3R)-3,5,7-Trihydroxy-2-[(2R,3S)-7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-1-benzofuran-5-yl]-2,3-dihydro-4H-chromen-4-one is a crystalline solid with a molecular weight of approximately 539.4 g/mol. It has a low solubility in water (less than 1 mg/mL) but is soluble in polar organic solvents such as methanol and acetonitrile. This compound is relatively stable under normal conditions but exhibits reactivity towards strong acids and bases. It is a chiral compound with potential enantiomeric selectivity in certain reactions.

This compound is typically synthesized via multistep organic synthesis involving the protected coupling of an appropriate phenolic starting material with a suitable benzofuran derivative, followed by various protecting group manipulations, reduction steps, and deprotection. The synthesis often requires the use of specific catalysts such as Lewis acids or transition metal complexes, and the yield is typically moderate to good, depending on the efficiency of the protecting group chemistry. The reaction conditions and selectivity are highly sensitive to the choice of reagents and solvents.

This compound is primarily used in the pharmaceutical industry for its potential as a drug candidate due to its structural complexity and bioactivity. It may also find applications in the polymer industry as a precursor or additive for specific polymer formulations. Additionally, it could be utilized in the development of sensors and semiconductors, although its specific applications in these fields are less well-documented.

When handling (2R,3R)-3,5,7-Trihydroxy-2-[(2R,3S)-7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-1-benzofuran-5-yl]-2,3-dihydro-4H-chromen-4-one, appropriate personal protective equipment (PPE) such as gloves and safety goggles should be worn. The substance should be handled in a well-ventilated area or a fume hood. In case of a spill, it should be immediately contained and cleaned up using appropriate absorbent materials. The Safety Data Sheet (SDS) should be consulted for detailed emergency procedures and storage requirements. The substance is not particularly hazardous under normal laboratory conditions, but care should be taken to avoid contact with skin and eyes.