5-Amino-2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid(CAS: 7164-43-4)

5-Amino-2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid is a white crystalline solid with a molecular weight of approximately 190.15 g/mol. It has a solubility of about 20 mg/mL in water and is sparingly soluble in ethanol. Chemically, it is relatively stable but can undergo hydrolysis under acidic conditions. It is not flammable but should be handled with care due to its potential reactivity.

5-Amino-2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid is typically synthesized via the condensation of 2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid with an amino compound such as an amine. The reaction is catalyzed by acids or bases, and the yield ranges from 50-70%. The reaction is selective and can be optimized to achieve higher purity.

5-Amino-2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid is used in various industries. It is a key intermediate in the synthesis of pharmaceuticals, particularly in the development of anti-cancer drugs and antibiotics. It is also used in the production of polymers, sensors, and semiconductors due to its unique chemical properties.

When handling 5-Amino-2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid, proper personal protective equipment (PPE) should be used, including gloves, goggles, and lab coat. It should be stored in a cool, dry place away from heat and direct sunlight. In case of spill, it should be handled according to the Material Safety Data Sheet (MSDS) guidelines, and the area should be well-ventilated. This compound is not flammable but can react under certain conditions, so it should be handled with caution.