(4-Iodophenyl)boronic acid(CAS: 5122-99-6)

(4-Iodophenyl)boronic acid is a white crystalline solid with a molecular weight of 289.96 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and acetone. It shows good reactivity in Suzuki coupling reactions and tends to form stable complexes with transition metals. This compound is commonly used as a reagent in organic synthesis due to its stability and functional groups.

(4-Iodophenyl)boronic acid is typically synthesized through the reaction of 4-iodophenol with boron trichloride in the presence of anhydrous aluminum chloride as a catalyst. The reaction is carried out in a chlorinated solvent, leading to high selectivity and good yield. This method allows for the formation of the desired product with minimal side reactions.

(4-Iodophenyl)boronic acid is widely used in the pharmaceutical, polymer, and semiconductor industries. In pharmaceuticals, it serves as a building block for drug synthesis. In polymers, it is used in the development of functional polymers with specific properties. In semiconductors, it plays a role in the fabrication of electronic devices due to its ability to form stable complexes with metal ions.

When handling (4-Iodophenyl)boronic acid (CAS: 5122-99-6), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be stored in a fume hood to prevent inhalation. In case of a spill, immediately clean it up with water and dispose of the waste according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.