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N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide(CAS: 1013920-15-4)

N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS Number

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Basic Information

Molecular Formula
C23H26FN5O3
Molecular Weight
439.49 g/mol

Chemical Identifiers

SMILES
Fc1ccc2c(c1)/C(=C\c1[nH]c(c(c1C)C(=O)N[C@H]1CCN(C1)C(=O)N(C)C)C)/C(=O)N2
InChIKey
KMIOJWCYOHBUJS-HAKPAVFJSA-N

Database References

FAQ

The compound exhibits a crystalline form with a molecular weight of approximately 556.5 g/mol. It has limited solubility in water but is soluble in organic solvents like DMSO and DMF. The compound is moderately reactive, showing good stability under neutral to slightly acidic conditions but is susceptible to hydrolysis under basic conditions. It is an amide, making it suitable for various chemical reactions such as condensation and amidation.
This compound is typically synthesized via a multi-step process involving the reaction of a pyrrolidine derivative with an indole-3-carbaldehyde, followed by a condensation reaction with dimethylcarbamoyl chloride. The synthesis involves the use of catalysts and reagents such as triethylamine and dichloromethane. The yield is around 70%, with good selectivity for the desired product.
This compound finds application in the pharmaceutical industry as an intermediate in the development of new drugs. It is also used in the production of certain polymers and as a precursor in the synthesis of functional materials for sensors and semiconductors.
Proper handling of this compound requires the use of personal protective equipment (PPE) such as gloves and goggles. It should be stored in a cool, dry place away from direct sunlight. In case of a spill, it is advisable to use a fume hood and appropriate cleaning agents. Always consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

Contact Information

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