2-amino-N-(2,2,2-trifluoroethyl)acetamide hydrochloride(CAS: 1171331-39-7)

2-amino-N-(2,2,2-trifluoroethyl)acetamide hydrochloride is a white crystalline solid with a molecular weight of approximately 245.96 g/mol. It has a high solubility in water and methanol. The compound is moderately reactive, particularly in acidic conditions. It is stable under normal storage conditions but should be protected from strong bases and oxidizing agents.

2-amino-N-(2,2,2-trifluoroethyl)acetamide hydrochloride is typically synthesized by reacting 2-amino-N-(2,2,2-trifluoroethyl)acetamide with hydrochloric acid in an aqueous solution. The reaction is carried out to high selectivity and yields a pure product. Commonly used methods include the use of concentrated hydrochloric acid at room temperature for a few hours.

2-amino-N-(2,2,2-trifluoroethyl)acetamide hydrochloride is primarily used in the pharmaceutical industry as a precursor for the synthesis of various medicinal compounds. It is also utilized in the polymer industry for developing novel materials with specific properties. Its application in sensors and semiconductors is also being explored due to its unique chemical properties.

When handling 2-amino-N-(2,2,2-trifluoroethyl)acetamide hydrochloride, it is important to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place, away from direct sunlight and heat sources. Proper ventilation should be maintained to avoid exposure to fumes. In case of a spill, it should be cleaned up carefully, and the SDS (Safety Data Sheet) should be consulted for specific instructions.