3,4-Dichloro-2,5-furandione(CAS: 1122-17-4)

3,4-Dichloro-2,5-furandione (CAS: 1122-17-4) is a crystalline solid with a molecular weight of approximately 191.03 g/mol. It has a low solubility in water (0.025 g/100 mL at 25°C). This compound is reactive, especially towards nucleophiles, and can undergo ring-opening reactions. It is stable under normal conditions but requires storage in a desiccator to prevent moisture absorption.

3,4-Dichloro-2,5-furandione is typically synthesized via the condensation of chloromethylene furan with formaldehyde in the presence of a strong base like potassium tert-butoxide. The yield is moderate, around 50-60%, and the reaction is highly selective. This method requires careful handling and a fume hood due to the volatility and reactivity of intermediates.

3,4-Dichloro-2,5-furandione (CAS: 1122-17-4) is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry for the modification of polymer properties and in the development of advanced materials. Additionally, it has applications in the production of sensors and as a precursor in semiconductor manufacturing.

When handling 3,4-Dichloro-2,5-furandione (CAS: 1122-17-4), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a well-ventilated area and a desiccator to prevent moisture absorption. In case of a spill, use appropriate spill cleanup kits and ensure the area is well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.