4'-Chloro-2-biphenylamine(CAS: 1204-44-0)

4'-Chloro-2-biphenylamine is a white crystalline solid with a molecular weight of approximately 221.59 g/mol. It has poor water solubility but is soluble in common organic solvents like ethanol and acetone. This compound is moderately reactive and can undergo substitution reactions. It is slightly soluble in water and more soluble in organic solvents.

4'-Chloro-2-biphenylamine can be synthesized through a Friedel-Crafts alkylation reaction of 2-biphenylamine with chloromethylbenzene, catalyzed by aluminum chloride. The reaction yields high selectivity and moderate to good yields depending on reaction conditions.

4'-Chloro-2-biphenylamine is used in various industries, including pharmaceuticals for the synthesis of certain drugs, and in the production of dyes and pigments. It is also utilized in the manufacturing of polymers and as a precursor in the development of sensors and semiconductors.

Proper handling of 4'-Chloro-2-biphenylamine requires personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to avoid inhalation. Spills should be cleaned up with appropriate absorbents and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for specific handling and disposal information.